| Visions of Japan: Prints and Paintings from Cleveland Collections | | December | 12 | 2004 | April | 10 | 2005 |
| Project 244: From Leipzig: Works from the Ovitz Family Collection | | January | 30 | 2005 | May | 01 | 2005 |
| Masterworks from The Phillips Collection | Link | February | 20 | 2005 | May | 29 | 2005 |
| Drawn with Light: Pioneering French Photography from the Cleveland Museum of Art | | February | 26 | 2005 | June | 16 | 2005 |
| Project 244: Michael Borremans: Hallucination and Reality | Link | May | 22 | 2005 | September | 04 | 2005 |
| Highlights from the Permanent Collection | | June | 21 | 2005 | September | 12 | 2005 |
| The NEO Show | Link | July | 10 | 2005 | September | 04 | 2005 |
| Project 244: Needful Things: Recent Multiples | Link | September | 19 | 2004 | January | 02 | 2005 |
| Dukes & Angels: Art from the Court of Burgundy, 1364-1419 | Link | October | 24 | 2004 | January | 09 | 2005 |
| Ilya Kabakov Collaboration with Museum of Contemporary Art, Cleveland | | September | 01 | 2004 | January | 02 | 2005 |
| Luc Delahaye Photographs: History | | November | 06 | 2004 | February | 23 | 2005 |
| Draped in Splendor: Renaissance Textiles and the Church | | September | 07 | 2003 | September | 26 | 2004 |
| Drawing Modern: Works from the Agnes Gund Collection | Link | October | 26 | 2003 | January | 11 | 2004 |
| Jasper Johns: Numbers | Link | October | 26 | 2003 | January | 11 | 2004 |
| Assumed Identities: Nikki S. Lee Photographs | | November | 22 | 2003 | January | 21 | 2004 |
| Signs of Life: Recent Photography Acquisitions | | November | 22 | 2003 | April | 07 | 2004 |
| Object in Focus: Countess Szechenyi and Her Prestigious Kashmir Shawl | | November | 25 | 2003 | January | 04 | 2004 |
| Voyage of Discovery: The Landscape Photographs of Ray K. Metzker | Link | December | 07 | 2003 | February | 29 | 2004 |
| Project 244: Trenton Doyle Hancock: Moments in Mound History | | December | 14 | 2003 | April | 04 | 2004 |
| Aftermath: Laura Letinsky Still-Life Photographs | | January | 24 | 2004 | April | 07 | 2004 |
