| Burchfield to Schreckengost: Cleveland Art of the Jazz Age | | March | 28 | 2004 | July | 18 | 2004 |
| Tracing Light: Gary Fabian Miller Photographs | | April | 10 | 2004 | July | 21 | 2004 |
| Project 244: Kelly McLane: My Blue-Green Algae | Link | May | 01 | 2004 | August | 22 | 2004 |
| The Quilts of Gee's Bend | Link | June | 27 | 2004 | September | 12 | 2004 |
| Memory Quilt: Photographs of Gee's Bend by Arthur Rothstein and Marion Post Wolcott | | June | 27 | 2004 | September | 12 | 2004 |
| Trophies of the Hunt: Capturing Nature as Art | | July | 24 | 2004 | November | 03 | 2004 |
| Nature Sublime: Landscapes from the Nineteenth Century | | August | 15 | 2004 | November | 14 | 2004 |
| The NEO Show | Link | July | 10 | 2005 | September | 04 | 2005 |
| Project 244: Needful Things: Recent Multiples | Link | September | 19 | 2004 | January | 02 | 2005 |
| Dukes & Angels: Art from the Court of Burgundy, 1364-1419 | Link | October | 24 | 2004 | January | 09 | 2005 |
| Ilya Kabakov Collaboration with Museum of Contemporary Art, Cleveland | | September | 01 | 2004 | January | 02 | 2005 |
| Luc Delahaye Photographs: History | | November | 06 | 2004 | February | 23 | 2005 |
| Visions of Japan: Prints and Paintings from Cleveland Collections | | December | 12 | 2004 | April | 10 | 2005 |
| Project 244: From Leipzig: Works from the Ovitz Family Collection | | January | 30 | 2005 | May | 01 | 2005 |
| Masterworks from The Phillips Collection | Link | February | 20 | 2005 | May | 29 | 2005 |
| Drawn with Light: Pioneering French Photography from the Cleveland Museum of Art | | February | 26 | 2005 | June | 16 | 2005 |
| Project 244: Michael Borremans: Hallucination and Reality | Link | May | 22 | 2005 | September | 04 | 2005 |
| Highlights from the Permanent Collection | | June | 21 | 2005 | September | 12 | 2005 |
| Romantic Rebel: Anne-Louis Girodet, [Musee du Louvre] | Link | September | 19 | 2005 | January | 02 | 2006 |
| The Arts and Crafts Movement in Europe and America, 1880-1920: Design for the Modern World | Link | October | 16 | 2005 | January | 08 | 2006 |
