| Lynn Hershman Leeson: Cyborgs and Self-Promotion | | March | 10 | 2016 | August | 08 | 2016 |
| Masterworks on Loan, Celebrating the 100th Anniversary of the Cleveland Museum of Art, "White Tara" | Link | April | 06 | 2016 | November | 06 | 2016 |
| Stag at Sharkey's: George Bellows and the Art of Sports | | May | 14 | 2016 | September | 18 | 2016 |
| Masterworks on Loan, Celebrating the 100th Anniversary of the Cleveland Museum of Art, "Four Figures on a Step" by Bartolomé Estaban Murillo | Link | May | 10 | 2016 | July | 24 | 2016 |
| BIG: Photographs from the Collection | Link | June | 04 | 2016 | October | 09 | 2016 |
| Staff Art Show 2015 | | December | 17 | 2015 | December | 3 | 2016 |
| Art and Stories from Mughal India | Link | July | 31 | 2016 | October | 23 | 2016 |
| Masterworks on Loan, Celebrating the 100th Anniversary of the Cleveland Museum of Art, "Study for Portrait VI" by Francis Bacon | Link | October | 01 | 2016 | December | 31 | 2016 |
| Elegance and Intrigue: French Society in 18th-Century Prints and Drawings | | July | 16 | 2016 | November | 06 | 2016 |
| Dan Graham: Pavilion Compilation | | August | 13 | 2016 | December | 04 | 2016 |
| Dan Graham/Rocks | | August | 13 | 2016 | December | 04 | 2016 |
| Masterworks on Loan, Celebrating the 100th Anniversary of the Cleveland Museum of Art, "Portrait of Alfonso d'Avalos" by Titian | Link | December | 14 | 2015 | April | 04 | 2016 |
| Masterworks on Loan, Celebrating the 100th Anniversary of the Cleveland Museum of Art, "Bang" by Kerry James Marshall | Link | December | 15 | 2015 | March | 28 | 2016 |
| The Ecstasy of St. Kara | Link | September | 10 | 2016 | December | 31 | 2016 |
| Masterworks on Loan, Celebrating the 100th Anniversary of the Cleveland Museum of Art, "Mask (Kifwebe)" Congo, Luba | Link | March | 25 | 2016 | June | 13 | 2016 |
| Painting the Modern Garden: Monet to Matisse | Link | October | 11 | 2015 | January | 05 | 2016 |
| Shadows and Dreams: Pictorialist Photography in America | | September | 05 | 2015 | January | 17 | 2016 |
| Chinese Landscape Duets of Arnold Chang and Michael Cherney | Link | July | 12 | 2015 | February | 07 | 2016 |
| Jordan Wolfson: Two Early Videos | | December | 15 | 2015 | March | 06 | 2016 |
| Imagining the Garden | | October | 31 | 2015 | March | 06 | 2016 |
