| Masterworks on Loan, Celebrating the 100th Anniversary of the Cleveland Museum of Art, "Portrait of Emy" by Karl Schmidt-Rottluff | Link | August | 25 | 2016 | December | 18 | 2016 |
| Pharaoh: King of Ancient Egypt | Link | March | 13 | 2016 | June | 12 | 2016 |
| Masterworks on Loan, Celebrating the 100th Anniversary of the Cleveland Museum of Art, "Little Big Painting" by Roy Lichtenstein | Link | June | 28 | 2016 | November | 17 | 2016 |
| The Flowering of the Botanical Print | | March | 26 | 2016 | July | 03 | 2016 |
| Masterworks on Loan, Celebrating the 100th Anniversary of the Cleveland Museum of Art, Wade Family Tiffany Jewels | Link | September | 03 | 2016 | December | 31 | 2016 |
| Jon Pestoni: Some Years | | April | 23 | 2016 | July | 24 | 2016 |
| Converging Lines: Eva Hesse and Sol LeWitt | Link | April | 03 | 2016 | July | 31 | 2016 |
| Masterworks on Loan, Celebrating the 100th Anniversary of the Cleveland Museum of Art, "Nude Descending a Staircase (No. 2)" by Marcel Duchamp | Link | April | 05 | 2016 | July | 03 | 2016 |
| Ji Yun-Fei: Last Days of Village Wen | Link | February | 12 | 2016 | July | 31 | 2016 |
| Masterworks on Loan, Celebrating the 100th Anniversary of the Cleveland Museum of Art, "Onement IV" by Barnett Newman | Link | May | 03 | 2016 | August | 14 | 2016 |
| Lynn Hershman Leeson: Cyborgs and Self-Promotion | | March | 10 | 2016 | August | 08 | 2016 |
| Masterworks on Loan, Celebrating the 100th Anniversary of the Cleveland Museum of Art, "Royal Banquet for Celebration of the Fortieth Birthday and Thirty-Year Rule of King Sunjo" | Link | June | 06 | 2016 | October | 09 | 2016 |
| Stag at Sharkey's: George Bellows and the Art of Sports | | May | 14 | 2016 | September | 18 | 2016 |
| Masterworks on Loan, Celebrating the 100th Anniversary of the Cleveland Museum of Art, "White Tara" | Link | April | 06 | 2016 | November | 06 | 2016 |
| BIG: Photographs from the Collection | Link | June | 04 | 2016 | October | 09 | 2016 |
| Staff Art Show 2015 | | December | 17 | 2015 | December | 3 | 2016 |
| Masterworks on Loan, Celebrating the 100th Anniversary of the Cleveland Museum of Art, "Four Figures on a Step" by Bartolomé Estaban Murillo | Link | May | 10 | 2016 | July | 24 | 2016 |
| Art and Stories from Mughal India | Link | July | 31 | 2016 | October | 23 | 2016 |
| Elegance and Intrigue: French Society in 18th-Century Prints and Drawings | | July | 16 | 2016 | November | 06 | 2016 |
| Masterworks on Loan, Celebrating the 100th Anniversary of the Cleveland Museum of Art, "Study for Portrait VI" by Francis Bacon | Link | October | 01 | 2016 | December | 31 | 2016 |
