| Etchings by Charles A. Platt | | July | 07 | 1921 | September | 29 | 1921 |
| Special Exhibition of Work of Pupils in the Public Schools of Japan | | October | 28 | 1921 | November | 29 | 1921 |
| French Painting of the Latter 19th Century | Link | July | 12 | 1921 | September | 15 | 1921 |
| Fine Books and Bindings, designed and executed by Mrs. Rachel Hunt Miller | | November | 14 | 1921 | December | 02 | 1921 |
| Second Annual Exhibition of the Art and Craftwork of the Cleveland High Schools | | August | | 1921 | November | 20 | 1921 |
| Charles Shackleton Memorial Exhibition | | November | 15 | 1921 | December | 25 | 1921 |
| Etchings and Drypoints by Eileen and George Soper | | November | 16 | 1921 | December | 09 | 1921 |
| Western Etchings by George Elbert Burr, Charles W. Dahlgreen, Ralph M. Pearson, and B.[ror]J. Nordfelt | | November | 29 | 1921 | January | 05 | 1922 |
| Etchings of the Dutch Masters | | December | | 1922 | December | | 1922 |
| Special Exhibition of Paintings by Victor Charreton | | January | 01 | 1922 | February | 02 | 1922 |
| Durer | | December | | 1922 | December | | 1922 |
| Miniatures, Water Colors and Bronzes | | January | 03 | 1922 | March | 01 | 1922 |
| Etched Designs for Table China by Felix Bracquemond | | December | | 1922 | December | | 1922 |
| Dutch Graphic Arts | | January | 06 | 1922 | January | 30 | 1922 |
| Etchings by James McBey and Percy Smith | | December | | 1922 | December | | 1922 |
| 18th-Century Mezzotints | | February | 01 | 1922 | March | 21 | 1922 |
| Paintings by Chauncey F. Ryder | | February | 03 | 1922 | March | 01 | 1922 |
| Japanese Prints: Recent Additions to J. H. Wade | | February | 03 | 1922 | March | 18 | 1922 |
| Renaissance Art | | February | 12 | 1922 | April | | 1922 |
| Lithographs by Joseph Pennell and Henri Fantin-Latour | | March | 03 | 1922 | March | 23 | 1922 |
